Can Low Albumin Cause a Low Anion Gap?
Yes. Low albumin can result in a low anion gap, and it is one of the most common reasons a lab result looks unexpectedly low. If you are using an Anion Gap Calculator , the result may need an albumin correction before it is interpreted as a real indicator to an acid-base disorder. A low anion gap is often not the primary problem itself; it is usually a diagnostic clue that points to an underlying cause such as hypoalbuminemia, laboratory error, or another medical condi